SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15e066e62e12add29bad1031aefb51bd280cd56e73a96e09cd1b853a7e8251bd' 
  AND token = 'F91IqR0JqhLkVcKFGlvgUzZ18dOap4nxF3FbkZ+l+ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}