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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '732dfd2a667a534478a58a17d0cc74b0558f115513d990b7a1477088342d60d5' 
  AND token = 'KaB5W7q2cFph29AQ6N5qAnHS3UD7HC5tGRaSnQkHxaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}