SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e600f3afa76f6ba09d4e1a27cefc0d513307fab0c65efd50a23a1709f223967' 
  AND token = 'JUjgwiRiy8ux4i8ZV7DzrENOJLZawNjQPANH81G6ISY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}