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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5048e01725003aac23f585f1e7705fb1e7618f9315c62a7077f2326017549a32' 
  AND token = 'qa6GvwF3VyFPlbFcLA8Zy4+b9Klr+5aBv7CCiojCAms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}