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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f94b0cd8b04479de9d56593a9517287d60bb04fa16cee93caa7a93b93d6b360a' 
  AND token = 'zIVYEah4D37VKaHDEZUCF7a5JFitX5BM5m4vwEhmVm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}