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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54bdd15cadd9eb6c7c4842559f7c98191e578ef43eb615ad70c19fcc2289082a' 
  AND token = 'Jv4oVhiz8+CHcvFUsd2cOL/9ZNXkKp3hx7C09PjOTjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}