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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9a5f0f2a5e802cca1f41404fe5bc3032a25c527875a65f224f1c887ba1d96c9' 
  AND token = 'KB9Arh+coyBfByLmBHxDc7gu3+kQuMUiTk6UEzVkpg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}