SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c9f2a875e584b441e3caaec4fa8d87e39a80381d4d602fb3ea6c4a5369970da' 
  AND token = '54tDxHFitFTecfZY9xB2+u0KNlVIHJI6y1nN6j57MBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}