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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121ce46665aae115e92e5a3e79e0574776dd985a50661bc65da1d72a112ec526' 
  AND token = 'tsoFv8lo9sWo5YJnzdVtxUqK52D47vUKTgn5rusAX2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}