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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ab812e793141177079272901d99f3daed139e82effff3fe4d853ea613129209' 
  AND token = 'cXUkGbl1sYH11hEWXoDfnC2mfwyFXt7r4IZcx1GeCMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}