SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c1ba05deee1ff199b0e65637f7a9619205f68bd44edbfbe94956a017c41719a' 
  AND token = 'IQMHA/Pa+LeroosYGTEhV9MvOOLlKZ2yfZ/LQ8Xxz0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}