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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35133a8940ceb185da56f4e02f9a52f64a213f93ea73ca7e0f550ff5e85cbc47' 
  AND token = 'PpgNfpMAFnKoDb/lN7VaLvUdK4ka68QZ5yXiQM0ggz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}