SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2522949553128a7cb76148d5fc0c2efad7fa3560bf9e87637aa4faf5bedf9ff' 
  AND token = 'wzBV/AwK1+VYqSoO0vk7Rq+yqlgmSL5nvRpkHaND2To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}