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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6260f22dd63b975fca09d5b9a377dfcf07b45455d9445402df144ab698446dd' 
  AND token = 'D+5hr6PIkLqx2rk1WdNLqJOMHwM8jWX4dyv98S8JOLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}