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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e078f3a6c190fa9ffe84c8b5f448a305afca6a3c8d981d06ff42b3c2d35bde57' 
  AND token = 'sq6Yzw4JUfgdlyRCDWTCqDp4fepa3Iv8nNypCdPptOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}