SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a70e7ba236fe403b5082538f5f8e85eff6af464c3f202f8c6fc16c6007fca2b' 
  AND token = 'on4K7uU3mLkfo2Uqa/VvNtkh2gt/erQ/yyXOii3+N8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}