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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fa66c8c7c53908676c17fd25cd615484e9a9732399c1b55e82ad0b73dff5dc3' 
  AND token = 'NuYZqkFh5+HauEYHXAd4TzOyY7iaS/2g6R8K+rlhl/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}