SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed186e71e2c3ce917f4e62fb51c9e48e3b15e9c8e3629692142f15378de01e6a' 
  AND token = 'Yupnj+AFHC2q6JqmOpEYNfpoJ7UwFQ1DD0BrXPrA9Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}