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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99d5e98cfc0c57b7e845059fbd5b7bd9962b8ffbde803757024e0efbd90a6cfd' 
  AND token = 'j1Uaf23Wj5chvQU4++RqlIoByWt7ZAK8Z8lYx2KuHVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}