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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed222718c40bc675d6f2b2098616716908c7f4cf411e4edd65bd4d3e0d618130' 
  AND token = 'UdJgshGXpIQRxlS2hb7af2qg4gxS1YSgqeXNawEYa2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}