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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2307ff347e067134c1248ab367b55603366ee658e015917d54cf173219934211' 
  AND token = '8V2bAMon77HMGwqLI2pyXiXtFO3piQcfbohBCLRh3D8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}