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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ac71f405e9cba61a011e5a267bbf979f2d37d513c1f6037cf53596859b50fb4' 
  AND token = 'WadzIc8OPqFzNRCuAdrIIcvIfA2mlcpe/W2PfhLKnms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}