SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32043f72dabddecacd12e034f749f2e2a0a18fb93cd6d5616599c08c90b803d2' 
  AND token = '+AafxB+bUxqA1VFYP+aQZBm/4VA5cvSfHMn1CLNbYtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}