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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f4bf4552f2dc60f74d482add41b6125b326d3e9acbdc455e9059a6e157aecd' 
  AND token = 'XgbHKUq1GJGhp3NMAG1GHGV7pyRdU8aeQ9mSsth2G60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}