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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f583aba9e6d90e830195e3ace2f462e7e3f55ddcba8393b02013973515f432fa' 
  AND token = 'HTpJQjC/YDcT0xsUZkY0Qb1HdMTEHc3GekL8/Occ9pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}