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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ae43c798cd01ac0c7f67382e08a0b0d942d2c4fd98f1b588cbbe9513bf50b11' 
  AND token = '+MzISzL3KqbOdthIGgkkbnV4FKj/YfRK9j61adYyC5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}