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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49619e2ed94628a7f03d5bfb6a4b108383413bce9cd1dc886d46a8e96eff10eb' 
  AND token = 'acProYoC9JwmB3KFPTqlWVhtWGHT9WWhGpN2F321MQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}