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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebbf066bdc33d6cdd5f26a497821b216ab296df41e6b4bf1cf55fd4db99523c5' 
  AND token = 'LCMfM1IhVhYR3gczF9eoFCHtA8pVJ8Uv0/vI4UhNmM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}