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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ec592ea1020077ec15a75eb25400538e7e68f35ff93c29b7977ec645cd5ec36' 
  AND token = 'nb3xkkwES3fj20AVT/Kx59aACFsxS1/LuqnspdVEmL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}