SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5666fe5ece77cfec5f2f33d7f2824d9d7cfdb9e1845090dfda9c7f900fb2e487' 
  AND token = 'wSaJoMzd/i/VYYQBJH/LSficSoUSOfgAkhwtubC3d+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}