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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1acd99eb10927397c93293c5ab78bb586ddfb19755d459747ca95c7bd244b7d3' 
  AND token = 'AJ6eLgqo+M/S7Xq+0pjZh6njFeuTFa/v7XjCTSNyLWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}