SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4784b5d2d03a2c0174a57076c7ac1765152a5e837fa9b6ea2c86abbda2a2f217' 
  AND token = 'Vwt9o6ZYPI51a2mdRSI2vN4ur6Rc5Q0ctQiuFhUC07g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}