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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1abe63bf1f64687277ffddbb45792e3eb246a4b922b63d23508f6422283b50' 
  AND token = 'q7O/TzytqIvX1oISybPK+qX4toc6UXCBqbmIgs9OxYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}