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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a0fb1fa90869e44ec326af8357763f3121680f07058776f1314b1147cfe716' 
  AND token = 'Nt/y7v2a4Q52DAuJx9bv2HYSCuVDuw286KtNu2V0ZlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}