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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b33cc0965f7934d193389b77daa6c06e7d10f6d5e58c4ca8ecf18b7e6a1737' 
  AND token = 'JLOs6/Jw9ii0mbfmDnvkTCZj92bOB0IF1MIQA5bNaCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}