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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b79e0b33cca269aa1ca37a00fb3ae7aac1e33226807f1a6494fce08674acb441' 
  AND token = '4tFCmYEH2/LK4rLmhiDa79cpWa+gK22aNfYichMm4Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}