SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c2550bfcfc824b61286223161f5661687c391ea270d8ae579a6da17d9096acb' 
  AND token = 'XWtXAe59THyJh5vkHeIL43a231zXrfXw82DybI2RxDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}