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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72bcf849ebd5ac9a8f86c9424471ba1f303520a264f143c3605c9d642166c0e8' 
  AND token = '23gVjy2Cb81aKVrOmd7vvLFj/Lo1fem/LpLxGrBCRqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}