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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a72c84ebc47936847fcc0eed7ac1d1037655909362a0ee24bd1935f17d67ef' 
  AND token = 'iGXT6dYGgWZMVVAY7fPChrFLvRfM785x88H3uJYy0Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}