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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af89d0919901c66c8ea5eafad5df5caf0f6156699c0ffee3b26f4b118f705876' 
  AND token = 'Fh4voz1d87YIdECQtOUVLOTrk8iRKdDiPVtxoYFyZ3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}