SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f99d9f13340e2c034c6e777dbbce6072f910235276ed4e56360027f625c900' 
  AND token = 'NTkPWypz3I5NwU+VTgL7f+TJYc+cRXHObMqAi8rUn6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}