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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ce641d01256c526b7b7c765536a1bdeb1da1f6a1b307d737ff6bf7e9a37dd4a' 
  AND token = 'ehhOsnei1ywXzX4KF5f1WDPKUpLMWKuRXcQpRfuEARg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}