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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '608b5c563c24401c0e107ebae104e896ffeea88fb5cf2e27cb9455ff9ca01435' 
  AND token = 'r7EhusfaMSs5xi0j9zmF9phxVRRKN46eU2l7VbooCOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}