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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c47ade7853554835c19f9e56fa3505f5de6f73837e0e601fb9c569efa098181c' 
  AND token = 'O6ZH5+sJSvQSvRpeW/gZuD2RdHtvdCS8yvTJs7wEo/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}