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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e27f3e94c70031792f3830bf59f4141493edf1c420adf3401f7648edbfff6722' 
  AND token = 'YxS1J5DAHDNM4nlymMBl8Jbg+Gwf/Jbe3OZaGVRZ6vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}