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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffa2d625a94d5bf5f08ad109b1b58304614b6b3bf72da6c0082f1860c653814' 
  AND token = 'VAS/hIgDZf+eZGdeHqf6Fbyx95Yqe9gTydcWhuOaeVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}