SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a42d4638767665e74fa436b3d249544d9e660015f09beacafc3ccf116118b7' 
  AND token = 'LrqE7M7wC95PFyzyAMhuEYRY7mDTLbdcdP5xBZ7M+eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}