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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d8fcf43d0923aa4e2499304399f3e7122e17e21a3730d36dbebcd785bf9c3a' 
  AND token = 'eK0CiDqXd+WmNo0jMo+9zrIcVOnARORaxgi1cP3oK4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}