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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b078451263710936c1b4004dc95cbd12e87dac387e3de01b00f5bfd95c792f6' 
  AND token = 'MiLIWgOkWAO3sslL60PqoNe1a2DfALvZhUdWOnqGiMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}