SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca95c68a6951b4b2e96e5ff8ffa0b464a39c5f776b432ccb3cf997260ecb1522' 
  AND token = 'FFTO/RnbO65rkTq81/qdtj5f2GjsoWZGkF+yFpNYSMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}